In 1985, the laboratory became part of the branch of the Institute of Immunology of the Ministry of Health of the USSR under the name of the Laboratory of Immunomorphology. The first head of the laboratory was doctor of medical sciences, professor A.A. Botirbekov managed until 1994. Then the laboratory was headed by a doctor of medical sciences. A.R. Sirota until 2001. From 2002 to the present, the doctor of biological sciences, professor D.A. Musakhadjaeva. In 2018, the name of the laboratory was changed. 15 doctoral theses and 30 candidate theses were prepared and defended in this laboratory.

Additional directions:

– to study the mechanisms of immune response in children and adults living in ecologically unfavorable areas under normal conditions and in various pathological conditions;

– To study the mechanisms of immune reactions in children and adults with allergic, bronchopulmonary and gastrointestinal diseases;

– Study of the expression of immune response mediators in systemic diseases;

– To study the effects of immune response mediators and growth factors on regeneration and recovery from injuries;

– The trigger mechanism of immunopathogenesis in individuals of different ages who have recovered from coronavirus infection.

– The role of immunological and molecular genetic aspects of aging, longevity and the development of age-related pathologies.

During the laboratory activities, the following problems were studied:

– the influence of environmental factors on the state of human immunity;

– Immunological profile (normative indicators) of the population of different regions of the Republic of Uzbekistan;

– study of immune indicators in various pathological conditions (autoimmune diseases, metabolic diseases, consequences of radiation at the Chernobyl NPP, somatic diseases of children, acute and chronic respiratory diseases, TORCH infections, etc.).

The laboratory works in close cooperation with medical universities and research institutes in Uzbekistan, near and far abroad.

Musakhodjaeva Diloram Abdullayevna – Doctor of Biological Sciences, Professor

Field of research: fundamental and clinical immunology, environmental immunology, pediatrics, gynecology and obstetrics, infectious diseases, traumatology, ophthalmology and other areas.

BRIEF INFORMATION

Head of the Laboratory of Reproductive Immunology of the Institute of Immunology and Human Genomics of the Academy of Sciences of the Republic of Uzbekistan, Doctor of Biological Sciences, Professor, Musakhodjaeva Diloram Abdullayevna

Musakhodjaeva D.A. – a well-known scientist in the field of clinical immunology, highly respected in scientific circles both in our republic and abroad.

She heads the laboratory since 2002. Musakhodjaeva D.A. have been published more than 400 scientific works, including 8 monographs, as well as 1 patent on “Immunological criteria for predicting antenatal fetal death in pregnant women with diabetes” and 5 certificates for software issued by the Intellectual Property Agency. Republic of Uzbekistan. Also, 36 educational and methodological manuals, 2 information letters, 2 brochures and rationalization proposals were published.

Under the leadership of Musakhodjaeva D.A. to date, 10 highly qualified specialists have been trained, 3 of them are doctors of science, 7 are candidates of science.

Musakhodjaeva D.A. was the first in our Republic to identify changes in the immune system during menstruation in women, created the standard of indicators of the immune system, and revealed the mechanisms of the formation and changes of the immune system in women’s gynecological and obstetrical diseases. In these cases, it justifies the possibility of immunocorrection, and the recommended training manuals are widely used in practical medicine. Currently, scientific research of Musakhodjaeva D.A. includes basic and clinical immunology, environmental immunology, gynecology and obstetrics, infectious diseases, traumatology, ophthalmology, dermatovenerology and other fields.

Since 2011, Musakhodjaeva D.A. member of Medical Genetics Research Council; Allergology and Immunology; Molecular biology. Molecular genetics. Molecular biotechnology; Cell biology and developmental biology (in medical sciences), and from 2021 he is a member of the attestation commission for awarding a scientific title of the Bukhara State Medical Institute.

She taught courses of clinical allergology and immunology to students of the higher education system (as a professor of the microbiology department of Tashkent State Dental Institute).

Musakhodjaeva D.A. Awarded with “30 years of independence” and “Health care excellence of the Republic of Uzbekistan” badges.

Azizova Zukhra Shukhratovna – Senior Researcher, PhD

Keldiyorova Robiya Dilshodovna – laboratory assistant

Sarvinoz Erkinovna Doniyorova – laboratory assistant

• Study of indicators of innate and acquired immunity in women and men with various diseases of reproductive function.
• Conducting research to study the relationship between the effectiveness of immunotherapy and the state of the immune system in patients with various pathologies.
• Study of various genetic factors of predisposition to the development of diseases of mother and child.
• Monitoring the immune status of the population in various regions of Uzbekistan (Aral region, arid zones, etc.). Study of the influence of unfavorable factors on the development of secondary immunological deficiency.
• Development of new immunodiagnostic methods. Search for effective methods of immunocorrection and immunorehabilitation of immunodeficiency states using new immunotropic drugs.

2014. Research carried out by the institute’s team from 1992 to 2014. within the framework of budget topics financed by the State Committee for Science and Technology of the Republic of Uzbekistan, where all laboratories of the institute took part:

In 1992 1. “Monitoring the immune status of Chernobyl accident liquidators living on the territory of Uzbekistan”; 2. “Study of the immune status of the population of environmentally unfavorable regions of Uzbekistan and the development of immunotherapy methods,” which were sections of the topic “Study of the immune status of the population of various regions of Uzbekistan to identify the impact of environmental factors on human health and the development of immunotherapy methods.”

In 1993, “Study of the mechanisms of immunoregulation in chronic hepatitis against the background of intoxication with pesticides,” which is a section of the topic of the State Scientific and Technical Documentation 10.9.1. “Study of the immunological status of the population of various regions of Uzbekistan and the development of methods of immunotherapy and disease prevention” (together with the Research Institute of Occupational Diseases of the Ministry of Health of the Republic of Uzbekistan).

GSTP 5.1.3.1. “Study of the mechanisms of immunoregulation in children with reduced immunoreactivity” (together with the Research Institute of Pediatrics of the Ministry of Health of the Republic of Uzbekistan).

GSTP 6.1.1.3. “Development of immunological criteria for the diagnosis and prognosis of the course of autoimmune diseases”, which is section 6.1.1. “Research on immunological mechanisms and HLA genetic markers in patients with immunodeficiencies and autoimmune diseases and the development of effective methods of immunotherapy” (jointly with the Research Institute of Endocrinology of the Ministry of Health of the Republic of Uzbekistan).

GSTP 1.4.1. “The mechanism of formation of immunological deficiency of the population in the geoclimatic conditions of Uzbekistan”;

GNTP 1.4.2. “Immunological aspects of diagnosis, treatment and prevention of bacterial and viral infections in children” (together with the Research Institute of Pediatrics of the Ministry of Health of the Republic of Uzbekistan).

GSTP 3.2.5. “Immunological features of the development and course of chronic viral hepatitis in children” (together with the Research Institute of Pediatrics of the Ministry of Health of the Republic of Uzbekistan).

  “Immunoregulatory subpopulations of lymphocytes and the production of interleukins 1 and 2 in mothers and children with HBs-Ag carriage under the influence of immunocorrection,” which is a section of GNTP 5.1.16. “The relationship of immunological parameters and marker profiles of mother and child with HBs-Ag carriage under the influence of immunocorrection” (together with the Research Institute of AIH of the Ministry of Health of the Republic of Uzbekistan).

P-14.1.37. “Frequency and variety of immune system defects in women of reproductive age during viral infections (TORCH infections)” (2003-2005).

1. Research carried out within the framework of State programs for scientific activities of the Ministry of Innovative Development of the Republic of Uzbekistan:

F6-FK-1-11384 – The mechanism of molecular genetic control of the immune response in cervical intraepithelial neoplasia of the cervix. (2012-2014).

FA-A10. “Molecular genetic mechanism of the transition of acute bronchitis to the chronic form in children and the development of a differentiated approach to immunocorrection” (2015-2017).

FA-A-10-007. “Study of immunophenotype and Th1 and Th2 type cytokines for diagnosis and optimization of treatment of children with nephropathies” (2017-2018). The section of the topic on which the laboratory carried out the research institute was “Assess the state of the main parameters of the immune system, as well as the role of mediators of the immune response in children and their mothers.”

FA-A10. “Development of methods for differentiated immunocorrection, taking into account the immunoregulation of proliferative processes in women with endometriosis,” (2017-2018).

PZ-20170927383 “Assessment of immunogenetic factors in the development of fertility disorders of various origins in men and development of methods for a differentiated approach to the diagnosis and treatment of infertility” (2018 – 2019)

PZ-201906124. “Development of new biomarkers associated with variability in the pharmacological response in immune-mediated diseases to personalize their basic therapy” (2020-2021).

1. Research carried out at the expense of the Academy of Sciences of the Republic of Uzbekistan:

T.6-14 Fund for the Support of Basic Research of the Academy of Sciences of the Republic of Uzbekistan on the scientific project: Immunogenetic mechanisms in the pathogenesis of various forms of cystic fibrosis in children (2014 – 2015).

“Clinical and immunological criteria for predicting obstetric complications in women with covid-19 at various stages of gestation and in pregnant women who have had SARS COV-2 coronavirus infection in the pre-conception period” (2020-2022).

“The role of the immune system in the formation of endothelial dysfunction of the uteroplacental and fetal circulation” (2023-2025).

Fundamental project for 2025 – 2029. Project topic: “Determining the role of immunological and molecular genetic aspects of aging, longevity and the development of age-associated pathologies”

1. Monographs
2. With foreign partners:
3. Tuzankina I.A., Deryabina S.S., Bolkov M.A., Vlasova E.V., Krokhaleva Y.M., Cheremokhin D.A., Aripova T.U., Musakhodzhaeva D.A., Kamalov Z. .WITH. Primary immunodeficiencies (congenital errors of immunity) at an early age. Monograph. 2022., 232 p.

1. Republican monographs and textbooks:
2. D.A.Musakhodzhaeva, T.U.Aripova, Z.S.Kamalov, N.Ya.Faizullaeva. Immunobiological factors in women outside and during pregnancy // Monograph. Tashkent. 2020. 220 p.
3. Muzafarova S.A., Kamalov Z.S., Ismailov S.I., Musakhodzhaeva D.A. Ovarian form of hyperandrogenemia in women of reproductive age (immunological and endocrinological aspects). Monograph. Tashkent. 2021., 208 p.

B.Patents

1. Certificates for software products
2. 1 №DGU 04142.
3. №DGU 05554.
4. №DGU 05555.
5. №DGU 06257.
6. №DGU 06258.
7. №DGU 17615.
8. Articles (2012-2023)
9. In foreign publications:
10. Musakhodzhaeva D.A., Faizullaeva N.Ya., Shamsiev F.M., Dzhumaeva D.N., Azizova Z.Sh. Dynamics of immunological parameters in recurrent obstructive bronchitis in children under the influence of lycopid // Russian Journal of Immunology, 2015, No. 3 (1), t. 9 (18), pp. 144-146.
11. Musakhodzhaeva D.A., Faizullaeva N.Ya., Shamsiev F.M. Clinical and immunological characteristics of children with cystic fibrosis // Russian Journal of Immunology, 2015, No. 3 (1), v. 9 (18), pp. 229-232.
12. Shamsiev F.M., Faizullaeva. N.Ya., Musakhodzhaeva D.A. Dynamics of cytokines in children with cystic fibrosis as a result of therapy // XII National Congress with international participation “Current problems of cystic fibrosis”. Moscow, 2015. – P.90-91.
13. Musakhodzhaeva D.A. Faizullaeva N.Ya. Shamsiev F.M. Dzhumaeva D.N. Azizova Z.Sh. // Dynamics of immunological parameters in recurrent obstructive bronchitis in children under the influence of lycopid // Russian Immunological Journal, 2015, No. 3 (1), v. 9 (18), pp. 144-146.
14. Kalandarova A.N. Ataniyazova O.A. Musakhodzhaeva D.A. // Local synthesis of cytokines in women with cervical intraepithelial neoplasia against the background of human papillomavirus infection // Zh. Medical immunology. “Days of Immunology in St. Petersburg.” June 1-4, 2015 T.17, Special issue, P. 163.
15. Musakhodjaeva D.A. Fayzullaeva N.Ya.// The effectiveness of immunotherapy in children with cystic fibrosis// European Science Review. Austria, Vienna. October-November, 2016. – R.116-119
16. Fayzullaeva N.Ya. Shamsiev F.M. Musahodjaeva D.A. // The features of the immune status of children with chronic obstructive bronchitis on the background of cystic fibrosis // European Journal of Pharmaceutical and Medical Research EJPMR, 2016, 3(1), R. 190-193. (23) Scientific Journal IF, 4.161
17. Musakhodzhaeva D.A. Faizullaeva N.Ya. Azizova Z.Sh. Dzhumaeva D.N.// Dynamics of immunological parameters under the influence of immunocorrective therapy for respiratory diseases of the upper and lower respiratory tract // V Annual International Scientific and Practical Conference “Current Issues of Medicine”, Baku, Azerbaijan. April 39-30, 2016, – pp. 41-42.
18. Faizullaeva N.Ya. Musakhodzhaeva D.A. Dzhumaeva D.N. Azizova Z.Sh. // Clinical and immunological characteristics of children with cystic fibrosis // V Annual International Scientific and Practical Conference “Current Issues in Medicine”, Baku, Azerbaijan. April 39-30, 2016, – pp. 73-74.
19. Malikova D.B. Kurbanov D.D. Musakhodzhaeva D.A. // Assessment of local immunity during the inflammatory genesis of infertility // Russian Journal of Allergology, 2017, No. 1, P.85-
20. Musakhodzhaeva D.A. Aripova T.U. Mamadalieva Ya.S. Eshimbetova G.Z. Faizullaeva N.Ya. // Local level of pro-inflammatory cytokines in women with external genital endometriosis // Russian Journal of Allergology, 2017, No. 1, P.103-105

Kalandarova A.N. Musakhodzhaeva D.A. // Dynamics of immunological parameters in women with cervical diseases as a result of treatment // Russian Journal of Allergology, 2017, No. 1, P.55-57

12. Musakhodzhaeva D.A. Faizullaeva. N.Ya. Shamsiev F.M. Azizova Z.Sh. Dzhumaeva D.N. // Response of the system of cytokines and nonspecific protection factors in children with cystic fibrosis // XIII National Congress “Innovative achievements in the diagnosis and therapy of cystic fibrosis” with international participation. Moscow region, Sergiev Posad. April 27-28, 2017. – pp. 88-89.
13. Masharipova M.S., Musakhodzhaeva D.A. // Indicators of nonspecific protective factors in children with diseases of the bronchopulmonary system // Collection of international scientific articles “Modern science in the XXI century: Main problems and stages of development”, 2017, Volume 2, p.94-98 (RU-SCIENCE. Moscow).
14. Musakhodzhaeva D.A., Kalandarova A.N. // Dynamics of innate and adaptive immunity in women with cervical intraepithelial neoplasia as a result of immunocorrective therapy // Medical immunology. “Days of Immunology in St. Petersburg 2017”, Special issue. 2017. T.19. pp. 187-188.
15. Aripova T.U. Musakhodzhaeva D.A. Shoazizov N.Sh. Dzhumaeva D.N. // Immunomodulatory effect of polyoxidonium in frequently ill children // Medical immunology. “Days of Immunology in St. Petersburg 2017”, Special issue. 2017. T.19.
16. Isanbaeva L.M., Musakhodzhaeva D.A. // Immunogenetic analysis of the risk of developing uterine fibroids in indigenous women of Tashkent // Medical immunology. “Days of Immunology in St. Petersburg 2017”, Special issue. 2017. T.19.S. 160-161
17. Musakhodjaeva D.A. Aripova T.U. Ismoilova D.U. Fayzullaeva N.Ya.// The level of cytokines in the peritoneal fluid in women with external genital endometriosis// The 25th World Congress on COGI. Vienna, Austria. November 30-December 2, 2017. p. 133.
18. Musakhodjaeva D.A. Kalandarova A.N.// Changes in the state of the immune system in women with cervical intraepitelial neoplasia// The 25th World Congress on COGI. Vienna, Austria. November 30-December 2, 2017. p. 133.
19. Eshembetova G.Z. Musakhodjaeva D.A. Choriev K. Aripova T.U. Magzumova N.M. Ismoilova D.U. Djumayeva D.N. Azizova Z. Sh. //The level ofII. In

Republican publications

1. Kireev V.V., Zhapparov A.K., Musakhodzhaeva D.A. Features of immunological parameters and the state of the thymus in systemic lupus erythematosus // Journal of theoretical and clinical medicine -2015.-No. 4, Tashkent, P.124-126
2. Musakhodzhaeva D.A., Faizullaeva N.Ya., Kamalov Z.S., Polyarush S.V., Azizova Z.Sh., Dzhumaeva D.N. Changes in the parameters of innate and adaptive immunity in children with chronic bronchitis against the background of helminthic infestation // Journal of Theoretical and Clinical Medicine, 2016, No. 3, pp. 135-138
3. Musakhodzhaeva D.A. Faizullaeva N.Ya. Mamadalieva Ya.S. Dzhumaeva D.N. , Azizova Z.Sh. Nonspecific protective factors in children with diseases of the bronchopulmonary system // Journal of Theoretical and Clinical Medicine. – Tashkent, 2016. – No. 6. – pp. 86-88.
4. Faizullaeva N.Ya., Musakhodzhaeva D.A., Ruzibakieva M.R. Yarmukhamedov A.S., Azizova Z.Sh., Dzhumaeva D.N. Features of some parameters of the immune system in men with impaired fertility // Journal of Theoretical and Clinical Medicine -2018.-No. 4, Tashkent, P.105-106
5. Musakhodzhaeva D.A. Faizullaeva N.Ya. Shamsiev F.M. Azizova Z.Sh. Dzhumaeva D.N. // Evaluation of the effectiveness of the immunocorrective drug “Licopid” in children with chronic bronchitis // IX Congress of the Euro-Asian Respiratory Society, VII Congress of Pulmonologists of Central Asia, Tashkent, May 25-26, 2016 – pp. 260-261.
6. Aripova T.U. Musakhodzhaeva D.A. Eshimbetova G.Z. Azizova Z.Sh. // Activity of phagocytes in peritoneal fluid in patients with external genital endometriosis // J. Medical Immunology, 2017, volume 19, pp. 176-17
7. Musakhodzhaeva D.A. Aripova T.U. Faizullaeva N.Ya. Muzafarova S.A. Shoazizova N.Sh. Kalandarova A.N. Kasimova D. Kaipbekova G.K.// “Congenital and acquired components of the immune system”// Journal of Theoretical and Clinical Medicine, 2017, No. 2, pp. 16-20
8. Faizullaeva N.Ya. Musakhodzhaeva D.A. Khegay T.R. // Frequency of occurrence of CFTR gene mutations associated with cystic fibrosis in Uzbekistan // Journal of Theoretical and Clinical Medicine, 2017, No. 2, pp. 21-24
9. Masharipova M.S., Musakhodzhaeva D.A., Fayzullaeva N.Ya.// The state of the immune status in children with chronic bronchitis of various etiologies // Journal of Theoretical and Clinical Medicine, 2017, No. 6, P.58- 61.
10. Sharopov S.G., Musakhodzhaeva D.A., Inoyatov A.Sh. // Analysis of modern views on risk factors for the development of congenital malformations of the maxillofacial region // Tibbietdayangi kun ilmiy, marifiy-manaviy journal 2(26) 2019. P.325-329
11. Sharopov S.G., Inoyatov A.Sh., Musakhodzhaeva D.A// Polymorphism c677t of the methylenetetrahydrofolate reductase gene in congenital cleft lip and palate // Journal of Theoretical and Clinical Medicine No. 4, 2018, pp. 13-15
12. Ismoilova D.U., Musakhodzhaeva D.A., Magzumova N.M., Dzhumaeva D.N. // Correction with glucosaminylmuramyl dipeptide in complex therapy of external genital endometriosis in women with infertility // Collection of materials of the Republican scientific and practical conference with international participation “Current issues of maternal and child health, achievements and prospects” Bukhara, November 8-9, 2018, p.41
13. Faizullaeva N.Ya., Musakhodzhaeva D.A., Ruzibakieva M.R., Yarmukhamedov A.S., Nurmukhamedov B.B., Azizova Z.Sh., Dzhumaeva D.N.// The role of mediators of the immune response in primary infertility in men // Journal of Theoretical and Clinical Medicine, 2019, No. 4 P.64-67
14. Musakhodzhaeva D.A., Sultanov Z.F., Shamsiev // Characteristics of cytokine status in children with bronchopulmonary pathology // Journal of Theoretical and Clinical Medicine, 2019, No. 6 P. 19-22
15. Sharopov S.G., Musakhodzhaeva D.A. // Cytokine profile in the age aspect in practically healthy children // Journal of Theoretical and Clinical Medicine, 2019, No. 6 P. 26-29
16. Sharopov S.G., Musakhodzhaeva D.A., Inoyatov A.Sh// Assessment of polymorphism of folate cycle genes in the prognosis of the development of congenital cleft lip // Collection of materials of the IIIrd scientific and practical international congress “Current problems” We are dentistry and maxillofacial surgery” May 2-3, 2019 Tashkent, pp. 131-132
17. Sharopov S.G., Musakhodzhaeva D.A., Inoyatov A.Sh. // Cytokine profile in children with congenital cleft lip and palate living in the Bukhara region // Collection of materials of the IIIrd scientific-practical international congress “Current problems of dentistry and maxillofacial surgery” May 2-3, 2019 Tashkent, pp. 132-133

1. Methodological recommendations
2. Methodological recommendations
3. Musakhodzhaeva D.A., Khasanov S.A., Shoazizov N.N. “Diagnostic value of determining the level of certain cytokines in chronic sinusitis in frequently and long-term ill preschool children” Methodological recommendations // Tashkent 2018//
4. Faizullaeva N.Ya., Musakhodzhaeva D.A., Kamalov Z.S., Azizova Z.Sh., Dzhumaeva D.N. “Immune mechanisms in cystic fibrosis” Methodological recommendations // Tashkent 2016//
5. Musakhodzhaeva D.A., Faizullaeva N.Ya., Azizova Z.Sh. “Cystic fibrosis disease” Medical manual\\ Tashkent 2018//
6. Kalandarova A.N., Aripova T.U., Musakhodzhaeva D.A. “Diagnostic value of determining the level of pro-inflammatory cytokines in cervical intraepithelial neoplasia” Methodological recommendations // Tashkent 2019//
7. Kalandarova A.N., Aripova T.U., Musakhodzhaeva D.A. “Efficacy of immunocorrective therapy for cervical intraepithelial neoplasia” Methodological recommendations // Tashkent 2019//
8. Sharipov S.G., Inoyatov A.Sh., Musakhodzhaeva D.A “Diagnostic value of determining the level of cytokines in the development of congenital cleft lip and palate” Methodological recommendations // Bukhara 2019//
9. Sharipov S.G., Inoyatov A.Sh., Musakhodzhaeva D.A. “Method of integral assessment of the prognosis of the development of congenital cleft lip and palate in the context of risk factors of various nature” Methodological recommendations // Bukhara 2019//
10. Musakhodzhaeva D.A., Eshimbetova G.Z., Mukhamedova B.U., Azizova Z.Sh., Rustamova N.B. “Determination of clinical, immunological and biochemical criteria for the prognosis of obstetric complications in women with COVID-19 at different stages of pregnancy” Methodological recommendations // Tashkent-2022//
11. Yuldosheva G.R., Musakhodzhaeva D.A., Jabbarova Yu.K., Azizova Z.Sh., Khakimova G.B., Rustamova N.B. “Diagnostic criteria for assessing the synthesis of interferons in pregnant women who have had COVID-19 in the pre-conception period” Methodological recommendations // Tashkent-2022//
12. Azizova Z.Sh., Musakhodzhaeva D.A., Ruzibakieva M.R. “Diagnostic significance of cytokine status in infertile couples with primary infertility” Methodological recommendations // Tashkent-2022//
13. Musakhodzhaeva D.A., Amonov E.I. “Clinical and immunological features of rhinosinusitis against the background of COVID-19 in military personnel” Methodological recommendations // Tashkent-2023//
14. R.M.Ruzybakiev, M.V.Zalalieva, T.U.Aripova, Kh.A.Tashpulatov, A.V.Madzhidov, D.A.Musakhodzhaeva, D.A.Maksudov, Z.S.Kamalov, L.I.Mirkamalova, I.Sh.Muhammadiev, M.M.Abdurakhmanov. Characteristics of the immune status of the adult population in various regions of Uzbekistan. // Guidelines. Tashkent, 1995, 20 p.
15. T.U.Aripova, Z.S.Kamalov, M.T.Alimova, N.Ya.Faizullaeva, N.N.Salikhova. Standard values of the main indicators of the immune system in women of reproductive age. // Guidelines. Tashkent. 2006, -20 p.
16. T.U.Aripova, Z.S.Kamalov, M.T.Alimova, N.Ya.Faizullaeva, N.N.Salikhova. The state of the immune system in women of reproductive age with herpesvirus infection before and after immunocorrection with polyoxidonium. // Guidelines. Tashkent. 2006, -20 p.
17. T.U.Aripova, Z.S.Kamalov, M.T.Alimova, N.Ya.Faizullaeva, N.N.Salikhova. Reproduction yoshdagi ayollarda immun tizimi asosiy kўrsatkichlarining meyoriy miqdorlari // Methodological recommendations. Tashkent. 2006, -16 p.
18. T.U.Aripova, Z.S.Kamalov, A.V.Alimov, N.Ya.Faizullaeva, M.T.Alimova, N.T.Ortikbaeva, M.A.Razhabova. Clinical manifestations and characteristics of the immune system in respiratory chlamydial infection in children // Methodological recommendations. Tashkent. 2012, -23 p.

COOPERATION (universities, research institutes, centers)

The laboratory works in close cooperation with medical universities and research institutes of Uzbekistan, near and far abroad.

For many years of fruitful work, professional excellence and high personal achievements in the field of healthcare, science and training of highly qualified personnel, the effective implementation of modern modern technologies to increase the level of efficiency and quality of medical care to the population, D.A. Musakhodzhaeva was awarded the following awards:

2021 “30 years of independence”

2023 “Excellence in Health Care of the Republic of Uzbekistan”